Melissa
17.10.2007, 16:23
Also nach den ARA Kriterien finde ich ist nur die Ratio falsch. alles andere stimmt.
ARA criteria for diagnosis of systemic lupus erythematosus
Criterion Definition
Malar rash Fixed erythema, flat or raised, over the malar eminences, tending to spare the nasolabial folds
Discoid rash Erythematosus raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur in older lesions
Photosensitivity Skin rash as a result of unusual reaction to sunlight, by patient history or physician observation
Oral ulcers Oral or nasopharyngeal ulceration, usually painless, observed by a physician
Arthritis Nonerosive arthritis involving 2 or more peripheral joints, characterized by tenderness, swelling, or effusion
Serositis Pleuritis - convincing history of pleuritic pain or rub heard by a physician or evidence of pleural effusion OR
Pericarditis - documented by EKG, rub or evidence of pericardial effusion
Renal disorder Persistent proteinuria greater than 0.5 grams per day or greater than 3+ if quantitation not performed OR
Cellular casts - may be red cell, hemoglobin, granular, tubular, or mixed
Neurologic disorder Seizures OR psychosis - in the absence of offending drugs or known metabolic derangements (uremia, ketoacidosis, or electrolyte imbalance)
Hematologic disorder Hemolytic anemia - with reticulocytosis OR
Leukopenia - less than 4,000/mm3 total on two or more occasions OR
Lymphopenia - less than 1,500/mm3 on two or more occasions OR
Thrombocytopenia - less than 100,000/mm3 in the absence of offending drugs
Immunologic disorders Positive antiphospholipid antibody OR
Anti-DNA - antibody to native DNA in abnormal titer OR
Anti-Sm - presence of antibody to Sm nuclear antigen OR
False positive serologic test for syphilis known to be positive for at least six months and confirmed by Treponema pallidum immobilization or fluorescent treponemal antibody absorption test
Antinuclear antibody An abnormal titer of antinuclear antibody by immunofluorescence or an equivalent assay at any point in time and in the absence of drugs known to be associated with "drug-induced lupus" syndrome
ARA criteria for diagnosis of systemic lupus erythematosus
Criterion Definition
Malar rash Fixed erythema, flat or raised, over the malar eminences, tending to spare the nasolabial folds
Discoid rash Erythematosus raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur in older lesions
Photosensitivity Skin rash as a result of unusual reaction to sunlight, by patient history or physician observation
Oral ulcers Oral or nasopharyngeal ulceration, usually painless, observed by a physician
Arthritis Nonerosive arthritis involving 2 or more peripheral joints, characterized by tenderness, swelling, or effusion
Serositis Pleuritis - convincing history of pleuritic pain or rub heard by a physician or evidence of pleural effusion OR
Pericarditis - documented by EKG, rub or evidence of pericardial effusion
Renal disorder Persistent proteinuria greater than 0.5 grams per day or greater than 3+ if quantitation not performed OR
Cellular casts - may be red cell, hemoglobin, granular, tubular, or mixed
Neurologic disorder Seizures OR psychosis - in the absence of offending drugs or known metabolic derangements (uremia, ketoacidosis, or electrolyte imbalance)
Hematologic disorder Hemolytic anemia - with reticulocytosis OR
Leukopenia - less than 4,000/mm3 total on two or more occasions OR
Lymphopenia - less than 1,500/mm3 on two or more occasions OR
Thrombocytopenia - less than 100,000/mm3 in the absence of offending drugs
Immunologic disorders Positive antiphospholipid antibody OR
Anti-DNA - antibody to native DNA in abnormal titer OR
Anti-Sm - presence of antibody to Sm nuclear antigen OR
False positive serologic test for syphilis known to be positive for at least six months and confirmed by Treponema pallidum immobilization or fluorescent treponemal antibody absorption test
Antinuclear antibody An abnormal titer of antinuclear antibody by immunofluorescence or an equivalent assay at any point in time and in the absence of drugs known to be associated with "drug-induced lupus" syndrome